Define and classify buffer? Name the ICF buffer and ECF buffer?


Definition of a Buffer: A buffer is a solution that can resist changes in pH when small amounts of acid or base are added.

or

A buffer is a solution that maintains a stable pH by resisting changes when exposed to small amounts of acid or alkali.

Classification of Buffers:

Buffers can be classified based on their location, primary components, and pH range.

1. Classification based on location:

1.     Extracellular fluid (ECF): Bicarbonate buffer system

2.     Intracellular fluid (ICF):   Protein buffer system, Phosphate buffer system

2. Classification based on primary components:

1.     Acid-base buffers:   Composed of a weak acid and its conjugate base or a weak base and its conjugate acid.

2.     Salt buffers:   Formed by mixing a weak acid or base with its corresponding salt.

3. Classification based on pH range:

1.  Acidic buffers: Have a pH below 7 and are primarily used in acidic environments.

2. Neutral buffers: Have a pH of around 7 and are used in neutral environments.

3.  Alkaline buffers: Have a pH above 7 and are primarily used in alkaline environments.

Name the ICF buffer and ECF buffer:

1.  Intracellular (ICF) Buffer: 

a. Proteins, 

b. Amino acids, and 

c. Phosphates.

2.  Extracellular (ECF) Buffer: 

a. Bicarbonate ions and 

b. Carbonic acid.

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